PDB
9M3Q
Resolution
2.7 Å
Released
March 11, 2026
Receptor
taar13c
Class
A
Species
Danio rerio
Ligand
Function
SPERMIDINE
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
SPERMIDINE D112 3.32x32 TM3 polar (charge-charge)
SPERMIDINE D112 3.32x32 TM3 polar (hydrogen bond)
SPERMIDINE L113 3.33x33 TM3 hydrophobic
SPERMIDINE T116 3.36x36 TM3 Van der Waals
SPERMIDINE L192 45.52x52 ECL2 Van der Waals
SPERMIDINE D202 5.42x43 TM5 polar (charge-charge)
SPERMIDINE D202 5.42x43 TM5 polar (hydrogen bond)
SPERMIDINE T206 5.46x461 TM5 Van der Waals
SPERMIDINE W269 6.48x48 TM6 hydrophobic
SPERMIDINE W269 6.48x48 TM6 aromatic (pi-cation)
SPERMIDINE F272 6.51x51 TM6 hydrophobic
SPERMIDINE F273 6.52x52 TM6 Van der Waals
SPERMIDINE D292 7.36x35 TM7 polar (charge-charge)
SPERMIDINE D292 7.36x35 TM7 polar (hydrogen bond)
SPERMIDINE G295 7.39x38 TM7 Van der Waals
SPERMIDINE W296 7.40x39 TM7 aromatic (pi-cation)
SPERMIDINE Y299 7.43x42 TM7 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 K Q L Q ICL1ECL1 C W Y ECL1ICL2 P L Q Y P T R I ICL2ECL2 G L E E Y I A S V Y C M G G C T L Y F ECL2ICL3 Q N E N ICL3ECL3 F S T ECL3N-term M D L S S Q E Y D P S Q F C F P A V N N S C L K G T H N-termC-term L R I F E P N S S D I N L F T V C-term H V S T Q T V V Y L I L A S A M T V T V L G N S V V I I S I A H F T P T N I L V M S L A L A D L L L G L V V M P F S M I R S V D G Y G E T F C L L H T G F D L F L T S V S I F H L I F I A V D R H Q A V C F T I P V A W V M V M I S W S M A A F Y S Y G V V Y S K A N L E N A L W S V L D T L L T F F L P C S V M V G L Y A R I F V V A K K H I K S I T E A N E N V F K N P R R S E R K A A K T L G I V V G A F I L C W L P F F I N S L V D P Y I N P Y A L F D A F G W L G Y T N S T L N P I I Y G L F Y P W F S L I R K T L V T
Helix box plot — Download: PNG | SVG S N G L V T V T M A S A L I L Y V V T Q 1 M S L A L A D L L L G V L V M P F S M I R 2 F I L H F I S V S T L F L D F G T H L L 3 A W V M V M I S W S M A A F Y S Y G V V 4 Y L G V M V S C P L F F T L L T D L V S W 5 G I V V G A F I L C W L P F F I N S L V 6 I P N L T S N T Y G L W G F A D F L A 7

GPCRdb(A)
GPCRdb(A)
taar13c
TM3
3x32 3.32x32 D112
3x33 3.33x33 L113
3x36 3.36x36 T116
ECL2
45x52 45.52x52 L192
TM5
5x43 5.42x43 D202
5x461 5.46x461 T206
TM6
6x48 6.48x48 W269
6x51 6.51x51 F272
6x52 6.52x52 F273
TM7
7x35 7.36x35 D292
7x38 7.39x38 G295
7x39 7.40x39 W296
7x42 7.43x42 Y299