PDB
9P83
Resolution
3.2 Å
Released
March 25, 2026
Receptor
NTS1
Class
A
Species
Homo sapiens
Ligand
NTS8–13
Function
Agonist
Reference
10.1038/S41586-026-10120-7

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
NTS8–13 F127 2.65x64 TM2 hydrophobic
NTS8–13 H131 ECL1 polar (hydrogen bond with backbone)
NTS8–13 H131 ECL1 Van der Waals
NTS8–13 H132 ECL1 Van der Waals
NTS8–13 R323 6.55x55 TM6 Van der Waals
NTS8–13 F326 6.58x58 TM6 Van der Waals
NTS8–13 F326 6.58x58 TM6 polar (hydrogen bond with backbone)
NTS8–13 I329 6.61x61 TM6 polar (hydrogen bond with backbone)
NTS8–13 I329 6.61x61 TM6 Van der Waals
NTS8–13 S330 ECL3 Van der Waals
NTS8–13 D331 ECL3 Van der Waals
NTS8–13 W334 ECL3 polar (hydrogen bond)
NTS8–13 Y339 7.28x27 TM7 Van der Waals
NTS8–13 Y339 7.28x27 TM7 polar (hydrogen bond)
NTS8–13 Y342 7.31x30 TM7 Van der Waals
NTS8–13 Y342 7.31x30 TM7 polar (hydrogen bond)
NTS8–13 Y346 7.35x34 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G E Q N R S A D G Q H A G G L V C T P T I ECL2ICL3 Q V C T V G G E H S T F S M A I E ICL3ECL3 S D E Q W ECL3N-term M R L N S S A P G T P G T P A A D P F Q R A Q A G L E E A L L A P G F G N A S G N A S E R V L A A P S S E L D V N T N-termC-term P V W R R R R K R P A F S R K A D S V S S N H T L S S N A T R E T L Y C-term D I Y S K V L V T A V Y L A L F V V G T V G N T V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L T L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A V P M L F T M H T A T V K V V I Q V N T F M S F I F P M V V I S V L N T I I A N K L T V M V R Q A A E Q G P G R V Q A L R H G V R V L R A V V I A F V V C W L P Y H V R R L M F C Y I T P F L Y D F Y H Y F Y M V T N A L F Y V S S T I N P I L Y N L V S A N F L A L C F R H I T L A C
Helix box plot — Download: PNG | SVG T N G V T G V V F L A L Y V A T V L V K 1 G S L A L S D L L T L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A V P M 4 N L V S I V V M P F I F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I T S S V Y F L A N T V M Y F Y 7

GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM2
2x64 2.65x64 F127
TM6
6x55 6.55x55 R323
6x58 6.58x58 F326
6x61 6.61x61 I329
TM7
7x27 7.28x27 Y339
7x30 7.31x30 Y342
7x34 7.35x34 Y346