CHEMBL24665


SMILES NCCc1c[nH]c(-c2cccc(C(F)(F)F)c2)n1
InChIKey NFUYVKMAGIJYKB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 255.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 5.21 5.21 5.21 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 9.01 9.03 9.05 ChEMBL
H4 HRH4 Human Histamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 5.8 5.8 5.8 ChEMBL
H1 HRH1 Human Histamine A pIC50 6.0 6.0 6.0 ChEMBL
H1 HRH1 Human Histamine A pEC50 6.6 6.6 6.6 ChEMBL