SB 258719


SMILES CC1CCN(CC1)CC[C@H](N(S(=O)(=O)c1cccc(c1)C)C)C
InChIKey AGVNHDNTFYHZNL-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 Guide to Pharmacology
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.1 7.3 7.5 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database