Chembl31605


SMILES CO[C@]12C=CC3(CC14CCC(C)(C)[C@H]4O)C1Cc4ccc(O)c5c4C3(CCN1C)[C@@H]2O5
InChIKey BELNGJAALXEXDR-JPTYMVJOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 423.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.07 8.07 8.07 ChEMBL
δ OPRD Human Opioid A pEC50 7.73 7.73 7.73 ChEMBL
κ OPRK Human Opioid A pKi 8.89 8.89 8.89 ChEMBL
κ OPRK Human Opioid A pEC50 8.8 8.8 8.8 ChEMBL
μ OPRM Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
μ OPRM Human Opioid A pEC50 9.1 9.1 9.1 ChEMBL