CHEMBL293645


SMILES COc1ccc(Br)cc1-c1nc(CN2CCN(Cc3ccccc3)CC2)cs1
InChIKey LDQRJOZTSIXFDZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 457.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.98 4.98 4.98 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.88 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database