CHEMBL320331


SMILES c1ccc(COC[C@@H]2CC[C@H](c3c[nH]cn3)O2)cc1
InChIKey RETVAMKTDRMQFH-DZGCQCFKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.36 6.38 6.4 ChEMBL
H3 HRH3 Human Histamine A pKi 6.48 6.49 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.87 6.88 6.9 ChEMBL
H3 HRH3 Human Histamine A pEC50 6.7 6.71 6.72 ChEMBL