CHEMBL1180629


SMILES Oc1ccc2c(c1)OC(CNCc1ccccc1)CC2
InChIKey DWUAAOIZQFTYQP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.08 8.89 9.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.72 6.72 6.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.08 8.08 8.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.01 8.01 8.01 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database