OLOPATADINE


SMILES CN(C)CC/C=C1/c2ccccc2COc2ccc(CC(=O)O)cc21
InChIKey JBIMVDZLSHOPLA-LSCVHKIXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 337.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations H1

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKi 7.8 7.8 7.8 ChEMBL
H1 HRH1 Human Histamine A pKi 8.08 8.08 8.08 Drug Central
H1 HRH1 Guinea pig Histamine A pKi 8.11 8.11 8.11 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database