CHEMBL99142


SMILES COc1ccccc1N1CCN(CCn2c(C)nc3c4ccccc4nc-3c2O)CC1
InChIKey PTZPHMWEBRURCP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.68 7.68 7.68 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.39 9.39 9.39 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database