S-(R)-1-((2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl)-3-phenylpropyl ethanethioate


SMILES CC(=O)SC(CCC1=CC=CC=C1)C2C(N(C2=O)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O
InChIKey CFRFZOJZPLDJPP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 449.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 7.28 7.28 7.28 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.55 6.55 6.55 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database