ILOPROST


SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
InChIKey HIFJCPQKFCZDDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Mouse Prostanoid A pKi 7.68 7.68 7.68 PDSP Ki database
EP3 PE2R3 Mouse Prostanoid A pKi 7.66 7.66 7.66 PDSP Ki database
IP PI2R Mouse Prostanoid A pKi 7.96 7.96 7.96 PDSP Ki database
EP2 PE2R2 Mouse Prostanoid A pKi 5.8 5.8 5.8 PDSP Ki database
EP4 PE2R4 Mouse Prostanoid A pKi 5.64 5.64 5.64 PDSP Ki database
EP3 PE2R3 Bovine Prostanoid A pKi 6.58 6.58 6.58 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 7.96 7.96 7.96 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 7.25 7.25 7.25 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 5.73 6.14 6.55 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.99 5.99 5.99 PDSP Ki database
FP PF2R Human Prostanoid A pKi 6.21 6.21 6.21 PDSP Ki database
IP PI2R Human Prostanoid A pKi 7.96 7.96 7.96 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database