L-366,948


SMILES CCC(C)C(C(=O)C1(CCCN1C(=O)C(CC2=NC(N=C2)(C(=O)N3CCCCC3)C(=O)N4CCCCC4)N)C=O)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)N
InChIKey OCVKQRQVXSMCCJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 3
Rotatable bonds 14
Molecular weight (Da) 768.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Human Vasopressin and oxytocin A pKi 8.29 8.29 8.29 PDSP Ki database
OT OXYR Rat Vasopressin and oxytocin A pKi 9.1 9.12 9.15 PDSP Ki database
OT OXYR Rhesus macaque Vasopressin and oxytocin A pKi 8.19 8.19 8.19 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 6.09 6.29 6.49 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database