p-F-HHSiD


SMILES CCC(C)C(C(=O)NC(CC(=O)O)C(=O)O)NC(=O)C(CO)NC(=O)C(CC1=CN=CN1)NC(=O)C(CC2=CN=CN2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCN4
InChIKey RVTKNIPUELNCNR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 24
Molecular weight (Da) 851.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.65 7.68 7.7 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.88 6.89 6.9 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.8 7.8 7.81 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.5 7.5 7.5 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.03 7.03 7.03 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database