L-803,087


SMILES COC(=O)C(CCCN=C(N)N)NC(=O)CCCC1=C(NC2=C(C=C(C=C12)F)F)C3=CC=CC=C3
InChIKey OPNMQSFIGUSHDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKi 6.7 6.7 6.7 PDSP Ki database
SST2 SSR2 Human Somatostatin A pKi 5.33 5.33 5.33 PDSP Ki database
SST3 SSR3 Human Somatostatin A pKi 5.89 5.89 5.89 PDSP Ki database
SST4 SSR4 Human Somatostatin A pKi 9.15 9.33 9.7 PDSP Ki database
SST5 SSR5 Human Somatostatin A pKi 5.41 5.41 5.41 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database