R-(-)-2,3:[4,5-b]-2'-Aminothiazolo-10,11-dihydroxyaporphine


SMILES CN1CCC2=C3C1CC4=C(C3=CC5=C2SC(=N5)N)C(=C(C=C4)O)O
InChIKey GEGIIDSRIPIFFT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 0
Molecular weight (Da) 339.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.6 5.6 5.6 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.48 6.48 6.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database