4-(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol


SMILES C1CC(CCC1NC2=NC(=NC3=C2C=CN3)C4=CC=CC=C4)O
InChIKey RBZNJGHIKXAKQE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pKi 6.4 6.4 6.4 PDSP Ki database
A1 AA1R Human Adenosine A pKi 9.0 9.0 9.0 PDSP Ki database
A3 AA3R Human Adenosine A pKi 6.7 6.7 6.7 PDSP Ki database
A2B AA2BR Human Adenosine A pKi 5.4 5.4 5.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database