beraprost


SMILES CC#CCC(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC3=C(C=CC=C3CCCC(O)=O)[C@H]12
InChIKey CTPOHARTNNSRSR-APJZLKAGSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 8.21 8.21 8.21 Drug Central
EP4 PE2R4 Human Prostanoid A pKi 8.29 8.29 8.29 Drug Central
IP PI2R Rat Prostanoid A pKi 8.11 8.11 8.11 Drug Central
IP PI2R Mouse Prostanoid A pKi 8.11 8.11 8.11 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pIC50 8.08 8.08 8.08 Drug Central