cefapirin


SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSC1=CC=NC=C1)C2=O)C(O)=O
InChIKey UQLLWWBDSUHNEB-CZUORRHYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.26 8.26 8.26 Drug Central
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 8.32 8.32 8.32 Drug Central
α2C ADA2C Human Adrenoceptors A pIC50 8.33 8.33 8.33 Drug Central
D2 DRD2 Human Dopamine A pIC50 8.33 8.33 8.33 Drug Central
D4 DRD4 Human Dopamine A pIC50 8.3 8.3 8.3 Drug Central
H2 HRH2 Human Histamine A pIC50 8.28 8.28 8.28 Drug Central
δ OPRD Human Opioid A pIC50 8.3 8.3 8.3 Drug Central
κ OPRK Human Opioid A pIC50 8.28 8.28 8.28 Drug Central
μ OPRM Human Opioid A pIC50 8.27 8.27 8.27 Drug Central
SST4 SSR4 Human Somatostatin A pIC50 8.29 8.29 8.29 Drug Central
NK1 NK1R Human Tachykinin A pIC50 8.31 8.31 8.31 Drug Central
CB1 CNR1 Human Cannabinoid A pIC50 8.39 8.39 8.39 Drug Central
D3 DRD3 Human Dopamine A pIC50 8.34 8.34 8.34 Drug Central
NK2 NK2R Human Tachykinin A pIC50 8.31 8.31 8.31 Drug Central