CHEMBL1243394


SMILES FC(F)(F)c1ccc(SC[C@H](c2c[nH]cn2)C2CCNCC2)cc1
InChIKey HGLGWLWXYRAXPK-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.89 5.89 5.89 ChEMBL
H1 HRH1 Human Histamine A pKi 6.55 6.55 6.55 ChEMBL
H3 HRH3 Human Histamine A pKi 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 7.64 7.64 7.64 ChEMBL