CHEMBL1258457


SMILES CCOc1ccccc1N1CCN(CC(O)CN2C(=O)NC(=O)C2(c2ccccc2)c2ccccc2)CC1
InChIKey KRYMKJFSDYDRHS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.86 6.86 6.86 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 7.34 7.34 7.34 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.01 7.01 7.01 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database