CHEMBL130884


SMILES CC(Nc1ccccc1-c1ccccc1)C1=NCCN1
InChIKey QPAIAAWBFFTOPZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 265.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.94 5.94 5.94 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.15 6.15 6.15 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.42 5.42 5.42 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.03 7.03 7.03 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.41 6.41 6.41 ChEMBL