dynorphin A-(1-8) (Human) [3123]



dynorphin A-(1-8) (Human)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O
InChIKey WRPLGMBDXVBPEG-VGXZEHLRSA-N
Sequence YGGFLRRI
HELM PEPTIDE1{Y.G.G.F.L.R.(R,[dR]).I}$$$$V2.0

Chemical Properties

Hydrogen bond acceptors 12
Hydrogen bond donors 14
Rotatable bonds 31
Log P -2.555
Molecular weight (Da) 980.6
Stereochemistry info partial

Database connections

Structure pdb 8F7W
Model (AF2) κ δ μ
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

dynorphin A-(1-8) (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 8F7W
Model (AF2) κ δ μ
GPCRdb related ligands

Compound is not listed as a drug.