RS 39604


SMILES COc1cc(N)c(cc1C(=O)OCCCN1CCCCC1)Cl
InChIKey RLSGBCUXLRMTPF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 326.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.2 8.45 8.7 Guide to Pharmacology
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pIC50 7.31 7.31 7.31 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pEC50 7.52 7.52 7.52 ChEMBL