CHEMBL14208
SMILES | CC(C)Oc1ccccc1OC(C)C1=NCCN1 |
InChIKey | YQBKUZKHVPTFOO-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 5 |
Molecular weight (Da) | 248.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
α2B | ADA2B | Human | Adrenoceptors | A | pKi | 5.8 | 5.8 | 5.8 | ChEMBL |
α2C | ADA2C | Human | Adrenoceptors | A | pKi | 6.4 | 6.4 | 6.4 | ChEMBL |
α2A | ADA2A | Human | Adrenoceptors | A | pKi | 7.08 | 7.08 | 7.08 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
α2B | ADA2B | Human | Adrenoceptors | A | pEC50 | 5.76 | 5.76 | 5.76 | ChEMBL |
α2C | ADA2C | Human | Adrenoceptors | A | pEC50 | 7.0 | 7.0 | 7.0 | ChEMBL |