CHEMBL143967


SMILES CCCN(CCC)CCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12
InChIKey WWJQYDAINIQCOK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 392.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.61 6.83 7.06 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.72 7.08 7.44 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 6.18 6.18 6.18 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 6.77 6.77 6.77 ChEMBL