CHEMBL147463


SMILES CN1CCN(C2=Nc3cc(Cl)ccc3Oc3ncccc32)CC1
InChIKey XUSZOVSAUPFWTP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 328.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.52 6.52 6.52 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.75 6.75 6.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.69 6.69 6.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database