CHEMBL160266
SMILES | Clc1ccc(N2CCN(Cc3cnn4c(N5CCN(Cc6ccccc6)CC5)cccc34)CC2)cc1 |
InChIKey | GYWHDZIJHYATFG-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 500.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.82 | 5.82 | 5.82 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.75 | 6.75 | 6.75 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.19 | 6.29 | 6.4 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.39 | 6.39 | 6.39 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |