CHEMBL1548


SMILES NC1=Nc2ccc(Cl)c(Cl)c2CN1
InChIKey VBKOTIVQMCTTAQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 215.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.94 5.94 5.94 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database