5-benzyloxytryptamine
SMILES | NCCc1c[nH]c2c1cc(OCc1ccccc1)cc2 |
InChIKey | WKPDXBXNJWWWGQ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 2 |
Rotatable bonds | 5 |
Molecular weight (Da) | 266.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Ligand site mutations | 5-HT6 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2A | 5HT2A | Rat | 5-Hydroxytryptamine | A | pKi | 6.44 | 6.44 | 6.44 | PDSP Ki database |
5-HT6 | 5HT6R | Rat | 5-Hydroxytryptamine | A | pKi | 6.53 | 6.92 | 7.21 | PDSP Ki database |
5-HT6 | 5HT6R | Rat | 5-Hydroxytryptamine | A | pKi | 6.5 | 6.85 | 7.2 | Guide to Pharmacology |
5-HT7 | 5HT7R | Guinea pig | 5-Hydroxytryptamine | A | pKi | 5.96 | 6.28 | 6.59 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |