sarafotoxin S6b [7061]



sarafotoxin S6b


SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC2=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
InChIKey ZHRYDGYRZIWZPS-RAALVGGVSA-N
Sequence CSCKDMTDKECLYFCHQDVIW
HELM PEPTIDE1{C.S.C.K.D.M.T.D.K.E.C.L.Y.F.C.H.Q.D.V.I.W}$PEPTIDE1,PEPTIDE1,3:R3-11:R3|PEPTIDE1,PEPTIDE1,1:R3-15:R3$$$

Chemical Properties

Hydrogen bond acceptors 38
Hydrogen bond donors 34
Rotatable bonds 51
Log P -6.548
Molecular weight (Da) 2562.0
Stereochemistry info partial

Database connections

Structure pdb 6LRY
Model (AF2) ETA
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

sarafotoxin S6b


Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 6LRY
Model (AF2) ETA

Compound is not listed as a drug.