silodosin [7332]



silodosin


SMILES C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F
InChIKey PNCPYILNMDWPEY-QGZVFWFLSA-N

Chemical Properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 13
Log P 3.071
Molecular weight (Da) 495.2
Stereochemistry info full

Database connections

Structure pdb 9M4T
Model (Boltz2) α1B α1D α1A
Ligand site mutations α1A
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

silodosin


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 3
Phase III 3
Phase IV 3

Database connections

Structure pdb 9M4T
Model (Boltz2) α1B α1D α1A
Ligand site mutations α1A

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score