sovateltide [7400]



sovateltide


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)[C@@H](C)CC
InChIKey DXPHNGAMYPPTBJ-TZMIJSMNSA-N
Sequence DEEAVYFAHLDIIW
HELM PEPTIDE1{[*C(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O |$_R2;;;;;;;;;;;;;;;$|].E.E.A.V.Y.F.A.H.L.D.I.I.W}$$$$

Chemical Properties

Hydrogen bond acceptors 22
Hydrogen bond donors 23
Rotatable bonds 56
Log P -0.883
Molecular weight (Da) 1819.8
Stereochemistry info partial

Database connections

Structure pdb 6IGL 8HBD
Model (Boltz2) ETB
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

sovateltide


Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 3
Phase III 0
Phase IV 1

Database connections

Structure pdb 6IGL 8HBD
Model (Boltz2) ETB

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score