CHEMBL194659


SMILES CN(C)C[C@H]1CC2c3ccccc3Oc3ccc(F)cc3[C@H]2O1
InChIKey LGHLMADLDHUIJY-MQSINFNDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 313.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 6.7 6.7 6.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
H1 HRH1 Human Histamine A pKi 8.12 8.12 8.12 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.37 8.37 8.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database