CHEMBL208927


SMILES Cc1cccc(NC(=O)c2cccc(C#N)c2)n1
InChIKey HRIDAJBBAATPGT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 237.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.31 6.39 6.48 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.27 5.27 5.27 ChEMBL