Chembl2338756


SMILES CO[C@]12CC[C@@]3(C[C@@H]1[C@@](C)(O)C(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5
InChIKey IORJPTSIJDJGHA-DPJBPYIISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 453.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 8.9 8.9 8.9 ChEMBL
μ OPRM Rat Opioid A pKi 10.04 10.04 10.04 ChEMBL
κ OPRK Human Opioid A pEC50 9.34 9.34 9.34 ChEMBL
κ OPRK Human Opioid A pKi 9.96 9.96 9.96 ChEMBL