evocalcet
SMILES | OC(=O)Cc1ccc(cc1)N1CC[C@@H](C1)N[C@@H](c1cccc2c1cccc2)C |
InChIKey | RZNUIYPHQFXBAN-XLIONFOSSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 6 |
Molecular weight (Da) | 374.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | Yes |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CaS | CASR | Human | Calcium-sensing | C | pEC50 | 7.03 | 7.03 | 7.03 | Guide to Pharmacology |
CaS | CASR | Rat | Calcium-sensing | C | pIC50 | 7.51 | 7.51 | 7.51 | ChEMBL |
CaS | CASR | Human | Calcium-sensing | C | pEC50 | 7.03 | 7.03 | 7.03 | ChEMBL |
CaS | CASR | Human | Calcium-sensing | C | pEC50 | 8.15 | 8.15 | 8.15 | Drug Central |