P2Y13 receptor (p2y13_human)
FAMILY
Class A (Rhodopsin) Nucleotide receptors P2Y receptors P2Y13 receptor
GENE
P2RY13 (GPR86, GPR94, FKSG77)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
P2Y purinoceptor 13, P2Y13, G-protein coupled receptor 86, G-protein coupled receptor 94
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
T
|
A
|
A
|
I
|
R
|
R
|
Q
|
R
|
E
|
10 |
L
|
S
|
I
|
L
|
P
|
K
|
V
|
T
|
L
|
E
|
20 |
A
|
M
|
N
|
T
|
T
|
V
|
M
|
Q
|
G
|
F
|
30 |
N
|
R
|
S
|
E
|
R
|
C
|
P
|
R
|
D
|
T
|
40 |
TM1 | |||||||||
R
|
I
|
V
|
Q
|
L
|
V
|
F
|
P
|
A
|
L
|
50 |
Y
|
T
|
V
|
V
|
F
|
L
|
T
|
G
|
I
|
L
|
60 |
L
|
N
|
T
|
L
|
A
|
L
|
W
|
V
|
F
|
V
|
70 |
ICL1 | TM2 | ||||||||
H
|
I
|
P
|
S
|
S
|
S
|
T
|
F
|
I
|
I
|
80 |
Y
|
L
|
K
|
N
|
T
|
L
|
V
|
A
|
D
|
L
|
90 |
I
|
M
|
T
|
L
|
M
|
L
|
P
|
F
|
K
|
I
|
100 |
ECL1 | |||||||||
L
|
S
|
D
|
S
|
H
|
L
|
A
|
P
|
W
|
Q
|
110 |
TM3 | |||||||||
L
|
R
|
A
|
F
|
V
|
C
|
R
|
F
|
S
|
S
|
120 |
V
|
I
|
F
|
Y
|
E
|
T
|
M
|
Y
|
V
|
G
|
130 |
I
|
V
|
L
|
L
|
G
|
L
|
I
|
A
|
F
|
D
|
140 |
R
|
F
|
L
|
K
|
I
|
I
|
R
|
P
|
L
|
R
|
150 |
ICL2 | TM4 | ||||||||
N
|
I
|
F
|
L
|
K
|
K
|
P
|
V
|
F
|
A
|
160 |
K
|
T
|
V
|
S
|
I
|
F
|
I
|
W
|
F
|
F
|
170 |
L
|
F
|
F
|
I
|
S
|
L
|
P
|
N
|
T
|
I
|
180 |
ECL2 | |||||||||
L
|
S
|
N
|
K
|
E
|
A
|
T
|
P
|
S
|
S
|
190 |
V
|
K
|
K
|
C
|
A
|
S
|
L
|
K
|
G
|
P
|
200 |
TM5 | |||||||||
L
|
G
|
L
|
K
|
W
|
H
|
Q
|
M
|
V
|
N
|
210 |
N
|
I
|
C
|
Q
|
F
|
I
|
F
|
W
|
T
|
V
|
220 |
F
|
I
|
L
|
M
|
L
|
V
|
F
|
Y
|
V
|
V
|
230 |
I
|
A
|
K
|
K
|
V
|
Y
|
D
|
S
|
Y
|
R
|
240 |
ICL3 | TM6 | ||||||||
K
|
S
|
K
|
S
|
K
|
D
|
R
|
K
|
N
|
N
|
250 |
K
|
K
|
L
|
E
|
G
|
K
|
V
|
F
|
V
|
V
|
260 |
V
|
A
|
V
|
F
|
F
|
V
|
C
|
F
|
A
|
P
|
270 |
F
|
H
|
F
|
A
|
R
|
V
|
P
|
Y
|
T
|
H
|
280 |
ECL3 | TM7 | |||||||||
S
|
Q
|
T
|
N
|
N
|
K
|
T
|
D
|
C
|
R
|
|
290 |
L
|
Q
|
N
|
Q
|
L
|
F
|
I
|
A
|
K
|
E
|
300 |
T
|
T
|
L
|
F
|
L
|
A
|
A
|
T
|
N
|
I
|
310 |
C
|
M
|
D
|
P
|
L
|
I
|
Y
|
I
|
F
|
L
|
320 |
H8 | |||||||||
C
|
K
|
K
|
F
|
T
|
E
|
K
|
L
|
P
|
C
|
330 |
C-term | |||||||||
M
|
Q
|
G
|
R
|
K
|
T
|
T
|
A
|
S
|
S
|
340 |
Q
|
E
|
N
|
H
|
S
|
S
|
Q
|
T
|
D
|
N
|
350 |
I
|
T
|
L
|
G
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
ATP, ADP
STRUCTURE MODELS
STRUCTURES
No structures available