TAS2R16 (t2r16_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R16

GENE

Tas2r16 (Tas2r118, Tas2r18)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 16, T2R16, Candidate taste receptor mt2r40, T2R18

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
V
P
T
Q
V
T
I
F
S
10
                   
I
I
M
Y
V
L
E
S
L
V
20
                   
I
I
V
Q
S
C
T
T
V
A
30
                   
V
L
F
R
E
W
M
H
F
Q
40
ICL1 TM2      
R
L
S
P
V
E
T
I
L
I
50
                   
S
L
G
I
S
H
F
C
L
Q
60
                   
W
T
S
M
L
Y
N
F
G
T
70
      ECL1 TM3
Y
S
R
P
V
L
L
F
W
K
80
                   
V
S
V
V
W
E
F
M
N
I
90
                   
L
T
F
W
L
T
S
W
L
A
100
                   
V
L
Y
C
V
K
V
S
S
F
110
ICL2            
T
H
P
I
F
L
W
L
R
M
120
TM4              
K
I
L
K
L
V
L
W
L
I
130
                   
L
G
A
L
I
A
S
C
L
S
140
                   
I
I
P
S
V
V
K
Y
H
I
150
ECL2            
Q
M
E
L
V
T
L
D
N
L
160
                   
P
K
N
N
S
L
I
L
R
L
170
              TM5
Q
Q
F
E
W
Y
F
S
N
P
180
                   
L
K
M
I
G
F
G
I
P
F
190
                   
F
V
F
L
A
S
I
I
L
L
200
                   
T
V
S
L
V
Q
H
W
V
Q
210
          ICL3 TM6
M
K
H
Y
S
S
S
N
S
S
220
               
L
K
A
Q
F
T
V
L
K
S
230
                   
L
A
T
F
F
T
F
F
T
S
240
                   
Y
F
L
T
I
V
I
S
F
I
250
        ECL3 TM7
G
T
V
F
D
K
K
S
W
F
260
                 
W
V
C
E
A
V
I
Y
G
L
270
                   
V
C
I
H
F
T
S
L
M
M
280
  H8              
S
N
P
A
L
K
K
A
L
K
290
      C-term
L
Q
F
W
S
P
E
P
S

LINKS

UniProt

DIAGRAMS

ICL1 R L ICL1ECL1 P V L ECL1ICL2 S F T H P I F L W L R M ICL2ECL2 I Q M E L V T L D N L P K N N S L I L R L Q Q F E W Y F ECL2ICL3 S S ICL3ECL3 D K ECL3N-term M V N-termC-term W S P E P S C-term P T Q V T I F S I I M Y V L E S L V I I V Q S C T T V A V L F R E W M H F Q S P V E T I L I S L G I S H F C L Q W T S M L Y N F G T Y S R L F W K V S V V W E F M N I L T F W L T S W L A V L Y C V K V S K I L K L V L W L I L G A L I A S C L S I I P S V V K Y H S N P L K M I G F G I P F F V F L A S I I L L T V S L V Q H W V Q M K H Y S N S S L K A Q F T V L K S L A T F F T F F T S Y F L T I V I S F I G T V F K S W F W V C E A V I Y G L V C I H F T S L M M S N P A L K L L K K A Q F
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

C S Q V I I V L S E L V Y M I I S F I T 1 I S L G I S H F C L Q W T S M L Y N F G 2 W S T L W F T L I N M F E W V V S V K W 3 V L W L I L G A L I A S C L S I I P S V 4 I S A L F V F F P I G F G I M K L P N S 5 L A T F F T F F T S Y F L T I V I S F I 6 T F H I C V L G Y I V A E C V W F W S 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available