TAS2R43 (tr143_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R43

GENE

Tas2r143 (T2r36, Tas2r43)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 143, T2R143, Taste receptor type 2 member 43, T2R43, mT2R36

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
P
S
T
P
T
L
I
F
I
10
                   
I
I
F
Y
L
V
S
L
A
S
20
                   
M
L
Q
N
G
F
M
M
I
V
30
                   
L
G
R
E
W
M
R
N
R
T
40
ICL1 TM2      
L
P
A
A
D
M
I
V
A
S
50
                   
L
A
S
S
R
F
C
L
H
G
60
                   
I
A
I
L
A
N
L
L
A
S
70
    TM3          
F
D
F
C
Y
Q
A
N
L
I
80
                   
G
I
L
W
D
F
T
N
T
L
90
                   
I
F
W
L
T
A
W
L
A
I
100
                   
F
Y
C
V
K
I
S
S
F
S
110
ICL2            
H
P
V
L
F
W
L
K
W
R
120
TM4              
I
S
Q
L
V
P
R
L
L
V
130
                   
V
S
L
I
I
G
G
L
S
A
140
                   
V
I
S
A
T
G
N
F
M
A
150
ECL2            
N
Q
M
T
I
S
Q
G
F
H
160
                   
G
N
C
T
F
G
H
M
S
L
170
            TM5  
D
F
Y
R
Y
Y
Y
L
Y
H
180
                   
S
V
L
M
W
F
T
P
F
F
190
                   
L
F
L
V
S
V
I
V
L
M
200
                   
F
S
L
Y
Q
H
V
E
K
M
210
        ICL3    
R
G
H
R
P
G
P
W
D
L
220
TM6              
H
T
Q
A
H
T
M
A
L
K
230
                   
S
L
T
F
F
F
I
F
Y
I
240
                   
F
F
F
L
A
L
V
I
S
S
250
          ECL3 TM7
T
K
R
K
S
M
Q
S
Y
Y
260
               
W
A
R
E
A
I
I
Y
T
G
270
                   
I
F
L
N
S
I
I
L
L
F
280
  H8              
S
N
P
K
L
R
K
A
L
K
290
     
M
R
F

LINKS

UniProt

DIAGRAMS

ICL1 T L ICL1ICL2 S F S H P V L F W L K W ICL2ECL2 M A N Q M T I S Q G F H G N C T F G H M S L D F Y R Y Y ECL2ICL3 P G P W ICL3ECL3 M ECL3N-term M N-term P S T P T L I F I I I F Y L V S L A S M L Q N G F M M I V L G R E W M R N R P A A D M I V A S L A S S R F C L H G I A I L A N L L A S F D F C Y Q A N L I G I L W D F T N T L I F W L T A W L A I F Y C V K I S R I S Q L V P R L L V V S L I I G G L S A V I S A T G N F Y L Y H S V L M W F T P F F L F L V S V I V L M F S L Y Q H V E K M R G H R D L H T Q A H T M A L K S L T F F F I F Y I F F F L A L V I S S T K R K S Q S Y Y W A R E A I I Y T G I F L N S I I L L F S N P K L K M L R K A R F
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N Q L M S A L S V L Y F I I I F I L T 1 A S L A S S R F C L H G I A I L A N L L 2 W A T L W F I L T N T F D W L I G I L N 3 V P R L L V V S L I I G G L S A V I S A 4 V S V L F L F F P T F W M L V S H Y L Y 5 L T F F F I F Y I F F F L A L V I S S T 6 I S N L F I G T Y I I A E R A W Y Y S 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available