Number of structures, including multiple of same receptor (complex)

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 223 201 11 0 4 7 0
Receptor - ligand complexes 216 195 10 0 4 7 0
Receptor - G protein complexes 3 1 2 0 0 0 0
Active-state receptors* 37 35 2 0 0 0 0


Number of unique receptor complexes

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 47 40 4 0 2 1 0
Receptor - ligand complexes 46 40 3 0 2 1 0
Receptor - G protein complexes 3 1 2 0 0 0 0
Active-state receptors* 11 9 2 0 0 0 0
*Active state is defined as agonist-bound and opened intracellular TM bundle.

Specific sets of structures can be downloaded from the structure browser
Structure statistics was last updated: 2017-11-15



The number of unique crystallized receptors available. The number of unique receptors CRYSTAL STRUCTURES PUBLISHED each year. The number of crystal structures available each year.


Structural coverage of GPCR Classes


Class A
(Rhodopsin)




Class B1
(Secretin)

Class B2
(Adhesion)

Class C
(Glutamate)

Class F
(Frizzled)

Taste 2