Number of structures, including multiple of same receptor (complex)

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 252 224 13 0 6 9 0
Receptor - ligand complexes 245 218 12 0 6 9 0
Receptor - G protein complexes 4 1 3 0 0 0 0
Active-state receptors* 50 47 3 0 0 0 0


Number of unique receptor complexes

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors** 50 43 4 0 2 1 0
Receptor - ligand complexes 340 286 25 0 13 16 0
Receptor - G protein complexes 3 1 2 0 0 0 0
Active-state receptors* 15 13 2 0 0 0 0
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the structure browser
The latest released structure is from 2018-04-04



By class By ligand type The number of unique crystallized receptors available. The number of unique receptors GPCR-ligand complexes. The number of crystal structures available. The number of unique crystallized receptors available. The number of unique GPCR-ligand complexes. The number of crystal structures available.


Structural coverage of GPCR Classes


Class A
(Rhodopsin)




Class B1
(Secretin)

Class B2
(Adhesion)

Class C
(Glutamate)

Class F
(Frizzled)

Taste 2