Structure information

NOP receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4EA3

SPECIES

Homo sapiens

RESOLUTION

3.010

PREFERRED CHAIN

A

PUBLICATION DATE

April 25, 2012

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
compound 24 [PMID: 16451050] Q107 2.60x60 TM2 polar (hydrogen bond)
compound 24 [PMID: 16451050] I127 3.29x29 TM3 hydrophobic
compound 24 [PMID: 16451050] D130 3.32x32 TM3 polar (charge-charge)
compound 24 [PMID: 16451050] Y131 3.33x33 TM3 hydrophobic
compound 24 [PMID: 16451050] M134 3.36x36 TM3 hydrophobic
compound 24 [PMID: 16451050] I219 5.42x43 TM5 hydrophobic

Ligands

compound 24 [PMID: 16451050]

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Residue Diagrams

C N G L L G G V C V A L Y L G V I T V K 1 F N L A L A D T L V L L T L P F Q G T D 2 A T L T F T S T F M N Y Y D I A I V T K 3 A Q A V N V A I W A L A S V V G V P V A 4 Y C V S I V L V P V I F S F L F I C I A F 5 L V V V A V F V G C W T P V Q V F V L A 6 I P N L C S N V Y G L A T C F R L I A 7
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ICL1 T K M K ICL1ECL1 F W P F ECL1ICL2 P I R A L D V R ICL2ECL2 S A Q V E D E E I E C L V E I P T ECL2ICL3 R L L S G ICL3ECL3 V Q P S ECL3N-term M E P L F P A P F W E V I Y G S H L Q G N L S L L S P N H S L L P P H L L L N A S H G A F L P N-termC-term A S A L R R D V Q V S D R V R S I A K D V A L A C K T S E T V P R P A C-term L G L K V T I V G L Y L A V C V G G L L G N C L V M Y V I L R H T A T N I Y I F N L A L A D T L V L L T L P F Q G T D I L L G G N A L C K T V I A I D Y Y N M F T S T F T L T A M S V D R Y V A I C H T S S K A Q A V N V A I W A L A S V V G V P V A I M G P Q D Y W G P V F A I C I F L F S F I V P V L V I S V C Y S L M I R R L R G V S R E K D R N L R R I T R L V L V V V A V F V G C W T P V Q V F V L A Q G L G S E T A V A I L R F C T A L G Y V N S C L N P I L Y A F L D E N F R K F K A C F C C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NOP receptor
TM2
2x60 2.60x60 Q107
TM3
3x29 3.29x29 I127
3x32 3.32x32 D130
3x33 3.33x33 Y131
3x36 3.36x36 M134
TM5
5x43 5.42x43 I219