Structure information

P2Y1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4XNV

SPECIES

Homo sapiens

RESOLUTION

2.200

PREFERRED CHAIN

A

PUBLICATION DATE

April 1, 2015

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
BPTU F62 1.43x43 TM1 aromatic (edge-to-face)
BPTU L102 2.55x55 TM2 polar (hydrogen bond with backbone)
BPTU L102 2.55x55 TM2 polar (hydrogen bond with backbone)
BPTU P105 2.58x58 TM2 hydrophobic
BPTU A106 2.59x59 TM2 hydrophobic
BPTU F119 23.52x52 ECL1 aromatic (face-to-edge)
BPTU M123 3.24x24 TM3 hydrophobic

Ligands

BPTU

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Residue Diagrams

S N G L F G I I F V L I Y V A P L Y Y F 1 F N L A L A D F L Y V L T L P A L I F Y 2 C T L F L I S G Y L N V H F I F R Q L K 3 A I C I S V L V W L I V V V A I S P I L 4 Y C G L I L V L P V C F M A V T T C M S Y 5 V I I V L T V F V A S Y I P F H V M K T M 6 I P D V C S N L S A L G R T V Q Y T A 7
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ICL1 M K P W ICL1ECL1 K T D W I F ECL1ICL2 P L K S L G R L ICL2ECL2 G T G V R K N K T I T C Y D T T S D E Y ECL2ICL3 D L D N S ICL3ECL3 F Q T P A ECL3N-term M T E V L W P A V P N G T D A A F L A G P G S S W G N S T V A S T A A V S S S F K C A L T K T G N-termC-term K A S R R S E A N L Q S K S E D M T L N I L P E F K Q N G D T S L C-term F Q F Y Y L P A V Y I L V F I I G F L G N S V A I W M F V F H S G I S V Y M F N L A L A D F L Y V L T L P A L I F Y Y F N G D A M C K L Q R F I F H V N L Y G S I L F L T C I S A H R Y S G V V Y K K K N A I C I S V L V W L I V V V A I S P I L F Y S L R S Y F I Y S M C T T V A M F C V P L V L I L G C Y G L I V R A L I Y K P L R R K S I Y L V I I V L T V F A V S Y I P F H V M K T M N L R A R L D M C A F N D R V Y A T Y Q V T R G L A S L N S C V D P I L Y F L A G D T L S R F R R R A T R
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Residue Table


GPCRdb(A)
GPCRdb(A)
P2Y1 receptor
TM1
1x43 1.43x43 F62
TM2
2x55 2.55x55 L102
2x58 2.58x58 P105
2x59 2.59x59 A106
ECL1
23x52 23.52x52 F119
TM3
3x24 3.24x24 M123