Structure information

A2A receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5OM1

SPECIES

Homo sapiens

RESOLUTION

2.100

PREFERRED CHAIN

A

PUBLICATION DATE

Jan. 17, 2018

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol V84 3.32x32 TM3 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol L85 3.33x33 TM3 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol F168 45.52x52 ECL2 aromatic (face-to-face)
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol E169 ECL2 polar (charge-assisted hydrogen bond)
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol M177 5.38x40 TM5 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol W246 6.48x48 TM6 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol L249 6.51x51 TM6 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol H250 6.52x52 TM6 aromatic (face-to-edge)
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol N253 6.55x55 TM6 polar (hydrogen bond)
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol N253 6.55x55 TM6 polar (hydrogen bond)
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol I274 7.39x38 TM7 hydrophobic
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol H278 7.43x42 TM7 polar (hydrogen bond)

Ligands

4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

2D interaction plot

PoseView coming soon.

Residue Diagrams

V N G L I A L V A I A L E V T I Y V S S 1 V S L A A A D I A V G L V A I P F A I T I 2 A L L S F I S S Q T L V L V F C A I F L 3 A K G I I A I C W V L S F A I G L T P M 4 Y V G L M L L L P V L V C A F F N F Y V M Y 5 A I I V G L F A L C W L P L H I I N C F 6 F P N V V S N T H S L V I A L Y M L W 7
Download: PNG | SVG
ICL1 S N L Q ICL1ECL1 F C A ECL1ICL2 P L R Y N G L V ICL2ECL2 W N N C G Q P K E G K N H S Q G C G E G Q V A C L F E D V V ECL2ICL3 Q P L P G ICL3ECL3 P D C S H A ECL3C-term K A A G T S A R V L A A H G S D G E Q V S L R L N G H P P G V W A N G S A P H P E R R P N G Y A L G L V S G G S A Q E S Q G N T G L P D V E L L S H E L K G V C P E P P G L D D P L A Q D G A G V S C-term M P I M G S S V Y I T V E L A I A V L A I L G N V L V C W A V W L N N V T N Y F V V S L A A A D I A V G V L A I P F A I T I S T G A C H G C L F I A C F V L V L T Q S S I F S L L A I A I D R Y I A I R I T G T R A K G I I A I C W V L S F A I G L T P M L G P M N Y M V Y F N F F A C V L V P L L L M L G V Y L R I F L A A R R Q L K Q M E S E R A R S T L Q K E V H A A K S L A I I V G L F A L C W L P L H I I N C F T F F C P L W L M Y L A I V L S H T N S V V N P F I Y A Y R I R E F R K H V L P F F R Q T I I R S R Q Q E
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
A2A receptor
TM3
3x32 3.32x32 V84
3x33 3.33x33 L85
ECL2
45x52 45.52x52 F168
TM5
5x40 5.38x40 M177
TM6
6x48 6.48x48 W246
6x51 6.51x51 L249
6x52 6.52x52 H250
6x55 6.55x55 N253
TM7
7x38 7.39x38 I274
7x42 7.43x42 H278