Structure information

Y1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5ZBH

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

A

PUBLICATION DATE

April 25, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
BMS-193885 Q120 3.32x32 TM3 polar (hydrogen bond)
BMS-193885 C121 3.33x33 TM3 polar (hydrogen bond)
BMS-193885 I124 3.36x36 TM3 hydrophobic
BMS-193885 F173 4.60x61 TM4 hydrophobic
BMS-193885 T212 5.39x40 TM5 polar (hydrogen bond)
BMS-193885 T280 6.52x52 TM6 polar (hydrogen bond)
BMS-193885 F282 6.54x54 TM6 aromatic (edge-to-face)
BMS-193885 D287 6.59x59 TM6 polar (charge-assisted hydrogen bond)
BMS-193885 D287 6.59x59 TM6 polar (charge-assisted hydrogen bond)
BMS-193885 A294 ECL3 hydrophobic
BMS-193885 F302 7.35x34 TM7 hydrophobic

Ligands

BMS-193885

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Residue Diagrams

L N G S V G L I I V A G Y A L A L T F I 1 V N L S F S D L L V A M I C L P F T F V Y 2 L V L S F I S V T I S V C Q V F P N L K 3 A Y V G I A V I W V L A V A S S L P F 4 Y C I F I F C L P G F Y Q L V L L L T T Y 5 L S I V V A F A V C W L P L T I F N T V 6 I P N V C T S I M A T L H C L L F L L 7
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ICL1 K E M R ICL1ECL1 H W V F ECL1ICL2 P R G W R P ICL2ECL2 V M T D E P F Q N V T L D A Y K D K Y V C F D Q F P ECL2ICL3 K M R ICL3ECL3 H Q I I A ECL3N-term M N S T L F S Q V E N H S V H S N F S E K N A Q L L A F E N D D C H L N-termC-term N F C D F R S R D D D Y E T I A M S T M H T D V S K T S L K Q A S P V A F K K I N N N D D N E K I C-term P L A M I F T L A L A Y G A V I I L G V S G N L A L I I I I L K Q N V T N I L I V N L S F S D L L V A I M C L P F T F V Y T L M D G E A M C K L N P F V Q C V S I T V S I F S L V L I A V E R H Q L I I N N N R H A Y V G I A V I W V L A V A S S L P F L I Y Q S D S H R L S Y T T L L L V L Q Y F G P L C F I F I C Y F K I Y I R L K R R N N M M D D N K Y R S S E T K R I N I M L L S I V V A F A V C W L P L T I F N T V F D W N T C N H N L L F L L C H L T A M I S T C V N P I F Y G F L N K N L Q F F Q R D F F
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Residue Table


GPCRdb(A)
GPCRdb(A)
Y1 receptor
TM3
3x32 3.32x32 Q120
3x33 3.33x33 C121
3x36 3.36x36 I124
TM4
4x61 4.60x61 F173
TM5
5x40 5.39x40 T212
TM6
6x52 6.52x52 T280
6x54 6.54x54 F282
6x59 6.59x59 D287
TM7
7x34 7.35x34 F302