Structure information

μ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6DDE

SPECIES

Mus musculus

RESOLUTION

3.500

PREFERRED CHAIN

R

PUBLICATION DATE

June 13, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
DAMGO I144 3.29x29 TM3 hydrophobic
DAMGO D147 3.32x32 TM3 polar (charge-charge)
DAMGO Y148 3.33x33 TM3 aromatic (face-to-edge)
DAMGO M151 3.36x36 TM3 hydrophobic
DAMGO I296 6.51x51 TM6 hydrophobic
DAMGO V300 6.55x55 TM6 hydrophobic
DAMGO K303 6.58x58 TM6 polar (charge-assisted hydrogen bond)
DAMGO W318 7.35x34 TM7 hydrophobic
DAMGO Y326 7.43x42 TM7 polar (charge-assisted hydrogen bond)

Ligands

DAMGO

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Residue Diagrams

F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I V N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A G P G N I S D C S D P L A P A S C S P A P G S W L N L S H V D G N Q S D P C G P N R T G L G G S H S L C P Q T G S P S N-termC-term P T S S T I E Q Q N S A R I R Q N T R E H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M V T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G N I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I V N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L I T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
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Residue Table


GPCRdb(A)
GPCRdb(A)
μ receptor
TM3
3x29 3.29x29 I144
3x32 3.32x32 D147
3x33 3.33x33 Y148
3x36 3.36x36 M151
TM6
6x51 6.51x51 I296
6x55 6.55x55 V300
6x58 6.58x58 K303
TM7
7x34 7.35x34 W318
7x42 7.43x42 Y326