Structure information

AT1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6DO1

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

A

PUBLICATION DATE

Jan. 30, 2019

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
(Sar1,Ile8)-Angiotensin II Q15 N-term polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II D16 N-term polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II D17 N-term polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II D17 N-term polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II W84 2.60x60 TM2 hydrophobic
(Sar1,Ile8)-Angiotensin II V108 3.32x32 TM3 hydrophobic
(Sar1,Ile8)-Angiotensin II R167 4.64x65 TM4 polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II A181 45.51x51 ECL2 hydrophobic
(Sar1,Ile8)-Angiotensin II F182 45.52x52 ECL2 polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II F182 45.52x52 ECL2 polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II H183 ECL2 polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II Y184 ECL2 polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II Y184 ECL2 polar (hydrogen bond with backbone)
(Sar1,Ile8)-Angiotensin II K199 5.42x43 TM5 polar (charge-charge)
(Sar1,Ile8)-Angiotensin II D362 6.58x58 TM6 polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II D380 7.32x31 TM7 polar (charge-assisted hydrogen bond)
(Sar1,Ile8)-Angiotensin II M383 7.35x34 TM7 polar (hydrogen bond)
(Sar1,Ile8)-Angiotensin II I387 7.39x38 TM7 hydrophobic

Ligands

(Sar1,Ile8)-Angiotensin II

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

S N G F I G V V F I I S Y L T P I M V F 1 L N L A L A D L C F L L T L P L W A V Y 2 C T L L F V S A Y L N F S V S A S A I K 3 A K V T C I I I W L L A G L A S L P A 4 Y S T L I I L F P F L F G L I N K T L G L 5 M A I V L F F F F S W I P H Q I F T F L 6 L P N L C N N F Y A I C I T I P M A T 7
Download: PNG | SVG
ICL1 M K L K ICL1ECL1 Y R W P F ECL1ICL2 P M K S R L R R ICL2ECL2 N V F F I E N T N I T V C A F H Y E S Q N S T ECL2ICL3 Y E I Q K N K ICL3ECL3 I I R ECL3N-term M I L N S S T E D G I K R I Q D D C P K A G R N-termC-term P P K A K S H S N L S T K M S T L S Y R P S D N V S S S T K K P A P C F E V E C-term H N Y I F V M I P T L Y S I I F V V G I F G N S L V V I V I Y F Y T V A S V F L L N L A L A D L C F L L T L P L W A V Y T A M E G N Y L C K I A S A S V S F N L Y A S V F L L T C L S I D R Y L A I V H T M L V A K V T C I I I W L L A G L A S L P A I I H R L P I G L G L T K N I L G F L F P F L I I L T S Y T L I W K A L K K A P R N D D I F K I I M A I V L F F F F S W I P H Q I F T F L D V L I Q L G D C R I A D I V D T A M P I T I C I A Y F N N C L N P L F Y G F L G K K F L Q I F K R Y L L K Y
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
AT1 receptor
TM2
2x60 2.60x60 W84
TM3
3x32 3.32x32 V108
TM4
4x65 4.64x65 R167
ECL2
45x51 45.51x51 A181
45x52 45.52x52 F182
TM5
5x43 5.42x43 K199
TM6
6x58 6.58x58 D263
TM7
7x31 7.32x31 D281
7x34 7.35x34 M284
7x38 7.39x38 I288