GPCRdb

Ligand	Amino Acid	Generic Number	Segment	Interaction Type


S1I8	Q15		N-term	polar (hydrogen bond with backbone)
S1I8	Q15		N-term	Van der Waals
S1I8	D16		N-term	polar (charge-assisted hydrogen bond)
S1I8	D17		N-term	polar (charge-assisted hydrogen bond)
S1I8	D17		N-term	polar (hydrogen bond with backbone)
S1I8	R23		N-term	Van der Waals
S1I8	W84	2.60x60	TM2	Van der Waals
S1I8	W84	2.60x60	TM2	hydrophobic
S1I8	Y87	2.63x63	TM2	Van der Waals
S1I8	Y92		ECL1	hydrophobic
S1I8	Y92		ECL1	Van der Waals
S1I8	V108	3.32x32	TM3	Van der Waals
S1I8	V108	3.32x32	TM3	hydrophobic
S1I8	L112	3.36x36	TM3	Van der Waals
S1I8	L112	3.36x36	TM3	hydrophobic
S1I8	R167	4.64x65	TM4	polar (charge-assisted hydrogen bond)
S1I8	C180	45.50x50	ECL2	Van der Waals
S1I8	A181	45.51x51	ECL2	hydrophobic
S1I8	A181	45.51x51	ECL2	Van der Waals
S1I8	F182	45.52x52	ECL2	polar (hydrogen bond with backbone)
S1I8	F182	45.52x52	ECL2	Van der Waals
S1I8	H183		ECL2	polar (hydrogen bond)
S1I8	Y184		ECL2	polar (hydrogen bond with backbone)
S1I8	Y184		ECL2	Van der Waals
S1I8	K199	5.42x43	TM5	polar (charge-assisted hydrogen bond)
S1I8	H355	6.51x51	TM6	Van der Waals
S1I8	D362	6.58x58	TM6	polar (charge-assisted hydrogen bond)
S1I8	D380	7.32x31	TM7	polar (charge-assisted hydrogen bond)
S1I8	M383	7.35x34	TM7	polar (hydrogen bond)
S1I8	P384	7.36x35	TM7	Van der Waals
S1I8	I387	7.39x38	TM7	hydrophobic
S1I8	I387	7.39x38	TM7	Van der Waals
S1I8	Y391	7.43x42	TM7	Van der Waals