Structure information

OX1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6TP4

SPECIES

Homo sapiens

RESOLUTION

3.010

PREFERRED CHAIN

A

PUBLICATION DATE

Jan. 1, 2020

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
ACT-462206 I122 3.28x28 TM3 hydrophobic
ACT-462206 P123 3.29x29 TM3 hydrophobic
ACT-462206 F219 5.42x43 TM5 hydrophobic
ACT-462206 I314 6.51x51 TM6 hydrophobic
ACT-462206 S315 6.52x52 TM6 polar (hydrogen bond)
ACT-462206 N318 6.55x55 TM6 polar (hydrogen bond)

Ligands

ACT-462206

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Residue Diagrams

T N G V L A V V F V A V Y A A I L V W E 1 V N L S L A D V L V T I A C L P A S L L V 2 F S L T L V A V S V S V A Q L Y P I V K 3 A R G S I L G I W A V S L A I M V P Q 4 Y A M A M L G L P A L Y T V I F F C S H Y 5 M V V L L V F A L C Y L P I S V L N V L 6 I P N A A S N A Y V L W H S F T F C A 7
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ICL1 H H M R ICL1ECL1 S W L F ECL1ICL2 P L L F K S ICL2ECL2 E C S S V L P E L A N R T R L F S V C D E R W A D D ECL2ICL3 G T T S A L V R N W K R P S D Q L G D L E Q G L S G E P Q P R A R A ICL3ECL3 G M F R Q A S ECL3N-term M E P S A T P G A Q M G V P P G S R E P S P V P P D Y E D E F L R Y L W R D Y L Y P K Q Y N-termC-term G L G P C G S L K A P S P R S S A S H K S L S L Q S R C S I S K I S E H V V L T S V T T V L P C-term E W V L I A A Y V A V F V V A L V G N T L V C L A V W R N T V T N Y F I V N L S L A D V L V T A I C L P A S L L V D I T E G H A L C K V I P Y L Q A V S V S V A V L T L S F I A L D R W Y A I C H T A R R A R G S I L G I W A V S L A I M V P Q A A V M L Y P K I Y H S C F F I V T Y L A P L G L M A M A Y F Q I F R K L W G R Q I P F L A E V K Q M R A R R K T A K M L M V V L L V F A L C Y L P I S V L N V L K R V F D R E A V Y A C F T F S H W L V Y A N S A A N P I I Y N F L S G K F K A C L P F R E Q A F S C
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Residue Table


GPCRdb(A)
GPCRdb(A)
OX1 receptor
TM3
3x28 3.28x28 I122
3x29 3.29x29 P123
TM5
5x43 5.42x43 F219
TM6
6x51 6.51x51 I314
6x52 6.52x52 S315
6x55 6.55x55 N318