Structure information

GABAB2

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

6UO8

SPECIES

Homo sapiens

RESOLUTION

3.630

PREFERRED CHAIN

B

PUBLICATION DATE

June 10, 2020

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL112710 S247 N-term polar (hydrogen bond with backbone)
CHEMBL112710 S270 N-term polar (hydrogen bond with backbone)
CHEMBL112710 S270 N-term polar (hydrogen bond)
GS39783 M694 6.41x41 TM6 polar (hydrogen bond)
GS39783 Y697 6.44x44 TM6 hydrophobic
GS39783 N698 6.45x45 TM6 polar (hydrogen bond)
GS39783 N698 6.45x45 TM6 polar (hydrogen bond)
GS39783 Y789 hydrophobic
GS39783 Y810 polar (hydrogen bond)
GS39783 Y810 polar (hydrogen bond)
GS39783 Y810 polar (hydrogen bond)
GS39783 Y810 aromatic (face-to-edge)

Ligands

CHEMBL112710

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GS39783

3D interaction viewer Download PDB file

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Residue Diagrams

S A M I M G L I T L A S L I S Y L P L S 1 N L I I L G G M L S Y A S I F L F G L 2 A F M A G F A T T Y G V T L I W T R V T 3 L L V I V G G M L L I D L C I L I C W Q 4 A L F C G F L M L L G K Y A Y V I G L W 5 G M S V Y N V G I M C I I G A A V S F L 6 C L T I T S C F I I V L A V I C F Q V N 7
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ICL1 Q R N K L I K M S ICL1ECL1 D G S F V ECL1ICL2 N V K M K K K I I ICL2ECL2 P L R R T V E K Y S M E P D P A G R D I S I R P L L E H C E N T ECL2ICL3 S I P A L N ICL3ECL3 R D ECL3N-term M A S P R S S G Q P G P P P P P P P P P A R L L L L L L L P L L L P L A P G A W G W A R G A P R P P P S S P P L S I M G L M P L T K E V A K G S I G R G V L P A V E L A I E Q I R N E S L L R P Y F L D L R L Y D T E C D N A K G L K A F Y D A I K Y G P N H L M V F G G V C P S V T S I I A E S L Q G W N L V Q L S F A A T T P V L A D K K K Y P Y F F R T V P S D N A V N P A I L K L L K H Y Q W K R V G T L T Q D V Q R F S E V R N D L T G V L Y G E D I E I S D T E S F S N D P C T S V K K L K G N D V R I I L G Q F D Q N M A A K V F C C A Y E E N M Y G S K Y Q W I I P G W Y E P S W W E Q V H T E A N S S R C L R K N L L A A M E G Y I G V D F E P L S S K Q I K T I S G K T P Q Q Y E R E Y N N K R S G V G P S K F H G Y A Y D G I W V I A K T L Q R A M E T L H A S S R H Q R I Q D F N Y T D H T L G R I I L N A M N E T N F F G V T G Q V V F R N G E R M G T I K F T Q F Q D S R E V K V G E Y N A V A D T L E I I N D T I R F Q G S E P P K D K T I I L E Q L R K I N-termC-term T Q N Q K K E D S K T S T S V T S V N Q A S T S R L E G L Q S E N H R L R M K I T E L D K D L E E V T M Q L Q D T P E K T T Y I K Q N H Y Q E L N D I L N L G N F T E S T D G G K A I L K N H L D Q N P Q L Q W N T T E P S R T C K D P I E D I N S P E H I Q R R L S L Q L P I L H H A Y L P S I G G V D A S C V S P C V S P T A S P R H R H V P P S F R V M V S G L C-term S L P L Y S I L S A L T I L G M I M A S A F L F F N I K N S P Y M N N L I I L G G M L S Y A S I F L F G L S E K T F E T L C T V R T W I L T V G Y T T A F G A M F A K T W R V H A I F K K D Q K L L V I V G G M L L I D L C I L I C W Q A V D H M T I W L G I V Y A Y K G L L M L F G C F L A W E T R N V D S K Y I G M S V Y N V G I M C I I G A A V S F L T Q P N V Q F C I V A L V I I F C S T I T L C L V F V P K L I T L R T N P D A R R F A T Q N Q F
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Residue Table


GPCRdb(A)
GPCRdb(C)
GABAB2
TM6
6x39 6.41x41 M694
6x42 6.44x44 Y697
6x43 6.45x45 N698