Structure information

Y2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7DDZ

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Jan. 27, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JNJ-31020028 W116 23.50x50 ECL1 aromatic (face-to-edge)
JNJ-31020028 Q130 3.32x32 TM3 polar (hydrogen bond)
JNJ-31020028 V134 3.36x36 TM3 hydrophobic
JNJ-31020028 L183 4.60x61 TM4 hydrophobic
JNJ-31020028 Y219 5.38x39 TM5 hydrophobic
JNJ-31020028 S220 5.39x40 TM5 polar (hydrogen bond)
JNJ-31020028 L224 5.43x44 TM5 hydrophobic
JNJ-31020028 H285 6.52x52 TM6 polar (hydrogen bond)
JNJ-31020028 Q288 6.55x55 TM6 polar (hydrogen bond)
JNJ-31020028 Q288 6.55x55 TM6 polar (hydrogen bond)
JNJ-31020028 Q288 6.55x55 TM6 polar (hydrogen bond)
JNJ-31020028 F307 7.35x34 TM7 hydrophobic

Ligands

JNJ-31020028

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Residue Diagrams

S N G I V G L L I I S C Y A L I L V V Q 1 A N L A V A D L L V N L T C L P F T L T Y 2 V T L T I T S V Q V A L G Q A Y P V L H 3 S F L I I G L A W G I S A L L A S P L 4 Y S F S I I G L P L V Y L I L L S S L S Y 5 V C V V V V F A V S W L P L H A F Q L A 6 L P N A F T S C M A I I H F V T F I L 7
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ICL1 K S M R ICL1ECL1 E W K M ECL1ICL2 H L E S K I ICL2ECL2 E Y S L I E I I P D F E I V A C T E K W P G E E K ECL2ICL3 A A ICL3ECL3 S Q V L ECL3N-term M G P I G A E A D E N Q T V E E M K V E Q Y G P Q T T P R G E L V P D P E P E L I D S T K L I N-termC-term L D A I H S E V S V T F K A K K N L E V R K N S G P N D S F T E A T N V C-term E V Q V V L I L A Y C S I I L L G V I G N S L V I H V V I K F T V T N F F I A N L A V A D L L V N T L C L P F T L T Y T L M G G P V L C H L V P Y A Q G L A V Q V S T I T L T V I A L D R H R C I V Y S K R I S F L I I G L A W G I S A L L A S P L A I F R S I Y G T V Y S L S S L L I L Y V L P L G I I S F S Y T R I W S K L K N H V S P G N D H Y H Q R R Q K T T K M L V C V V V V F A V S W L P L H A F Q L A V D I D D L K E Y K L I F T V F H I I A M C S T F A N P L L Y G W M N S N F L S E Q R Y R K A A F R C
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Residue Table


GPCRdb(A)
GPCRdb(A)
Y2 receptor
ECL1
23x50 23.50x50 W116
TM3
3x32 3.32x32 Q130
3x36 3.36x36 V134
TM4
4x61 4.60x61 L183
TM5
5x39 5.38x39 Y219
5x40 5.39x40 S220
5x44 5.43x44 L224
TM6
6x52 6.52x52 H285
6x55 6.55x55 Q288
TM7
7x34 7.35x34 F307